Global Citizen co-founder and CEO Hugh Evans said the event aimed to honour the heroic efforts of healthcare workers doing life-saving work.
"One World: Together At Home aims to serve as a source of unity and encouragement in the global fight to end COVID-19," he said.
"Through music, entertainment and impact, the global live-cast will celebrate those who risk their own health to safeguard everyone else’s.”
Like Global Citizen, the Sydney Opera House aims to affect positive change by inspiring and strengthening the community through art and culture. Alongside a growing collective of businesses, governments and community organisations, the Opera House recently announced its commitment to the United Nations Global Goals, with a focus on championing inclusion, diversity and equality, and helping to safeguard our natural environment.